Table 1

Differently expressed genes in two microarrays studies using bronchial tissues of asthmatic and control subjects
Functional category Genes
Immune signaling molecules CX3CR1*, IL7R, CD14*, SFRP1, SCYA21, SDF1, TNFRSF7, TRA@, CD19, ALOX15*, NOS2A, SCYA5, IL2RB, IL1R2*
Extracellular proteins COL11A1, FMOD, MUC5AC£, MUC2£, COL2A1, AGC1, FBLN1, GPC3, MUC4£, SFRP4
Immune response IGKC, HLA-DPB1*, HLA-DQA1*, HLA-DQB1*, HLA-DRB4, TRBA£, MS4A1, IGHM, IGLJ3, CEACAM5, ERAP2, IGHG1*, IGJ, IGLA, IGKV1D-13
Intracellular signaling PTPRC,IFI6, ARHGEF16, PSPHL, GNB2, SYK£, PPP1R3C, PHLDA1, TYROBP, FKBP8, PIM2, FLRT3
Proteolytic enzymes CPA3*, GZMA, CTSC, CTSG£, PSMA6, TPSB1£, SERPINB2, SERPINB4*, SPINK5
Transmembrane proteins TM4SF3, KLRC3, LGALS7, NKG7, ARHGAP4, ADRA2A, CLCA2, CLDN10, KCNJ16
Free radical metabolism GPX3, GSTA2, CYBA*, CYBB, NQO1*
Gene transcription TCF21, ZNF38, LDB1, MAF, STAT5A
Cell growth and proliferation GAS1, IGFBP6, CORO1A, TRIM16, EMP3, OGN, S100A14, S100P, SFN
Cell adhesion molecules ITGB2, POSTN*
Complement components C1QB, C7£, CFD
Metabolic enzymes RBP4, ALDH3A1, FA2H, ADH1B, PIK3R1
Structural proteins KRT23, TNC£

* Genes associated with asthma, atopy or atopic asthma.

Association between these genes and asthma or asthma-related phenotype (atopy or allergic asthma) was already investigated in other articles using the SLSJ familial asthma study [10-12,45].

£ Protein related to asthma.

Vaillancourt et al.

Vaillancourt et al. BMC Research Notes 2012 5:630   doi:10.1186/1756-0500-5-630

Open Data