Vanishing left ventricular thrombus in a woman with peripartum cardiomyopathy: a case report
1 Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
2 Department of Radiology, St. Boniface General Hospital, University of Manitoba, Winnipeg, Manitoba, Canada
3 Section of Cardiology, Department of Internal Medicine, Faculty of Medicine, University of Manitoba, 409 Taché Avenue, Winnipeg, R2H 2A6, Manitoba, Canada
4 Institute of Cardiovascular Sciences, Department of Physiology, St. Boniface General Hospital, University of Manitoba, Winnipeg, Manitoba, Canada
5 Cardiology, Radiology and Physiology, Bergen Cardiac Care Centre, St. Boniface General Hospital, Winnipeg, R2H 2A6, Canada
BMC Research Notes 2012, 5:544 doi:10.1186/1756-0500-5-544Published: 2 October 2012
Peripartum cardiomyopathy (PPCM) is a rare cardiac disorder characterized by the development of heart failure in the last month of pregnancy or up to 5 months postpartum in women without other identifiable causes of cardiac failure. The combination of left ventricular (LV) systolic dysfunction and hypercoaguability can cause thromboembolic complications including intra-cardiac thrombi.
A 25-year-old Caucasian female with PPCM demonstrated multiple thrombi in the LV on transthoracic echocardiography. Following anticoagulation with parenteral heparin, a cardiac MRI four days later demonstrated near resolution of the thrombi.
We review the presentation, diagnosis and management of LV thrombi in the clinical setting of PPCM.