Open Access Research article

Studies of the transmissibility of the agent of bovine spongiform encephalopathy to the domestic chicken

Jo Moore13, Stephen AC Hawkins1, Anthony R Austin1, Timm Konold1, Robert B Green1, Ian W Blamire1, Ian Dexter1, Michael J Stack1, Melanie J Chaplin1, Jan PM Langeveld4, Marion M Simmons1*, Yvonne I Spencer1, Paul R Webb1, Michael Dawson2 and Gerald AH Wells1

Author Affiliations

1 Department of Pathology and Host Susceptibility, Animal Health and Veterinary Laboratories Agency, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK

2 Centre for Epidemiology and Risk Analysis, Animal Health and Veterinary Laboratories Agency, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK

3 School of Veterinary and Biomedical Sciences, Murdoch University, South Street, Murdoch, WA 6150, Australia

4 Central Veterinary Institute of Wageningen UR (CVI), P.O. Box 65, 8200, AB Lelystad, Netherlands

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BMC Research Notes 2011, 4:501  doi:10.1186/1756-0500-4-501

Published: 17 November 2011

Additional files

Additional file 1:

Female chicken, number 979, at 1270 days post parenteral inoculation (primary exposure study). It is first seen feeding from a trough (time 8:40 is displayed in the left bottom corner of the clip). It then retreats with its eyes closed and appears to sleep, sitting down with its head resting on the side of the trough. At 8:44, it wakes up, moves its head and gets up before feeding again from the trough.

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Additional file 2:

Female chicken, number 980, at 1256 days post parenteral inoculation (primary exposure study). This chicken has difficulty maintaining balance as can be seen when it is pushed to the side or encouraged to move. It is generally reluctant to walk and has a tendency to stand with flexed intertarsal joints. By comparison, chicken 989, which was at the same time point post inoculation when filmed and is shown in the overlaid video clip, walks without difficulty and stands upright.

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