Table 3

Detection of copy number of specific regions

Platform

0n: CDKN2A

TC-32

1n: 9p21.3-p21.2

TC-32

3n: Chr 8

TC-32

4n: 1q

TC-32

>10n: MDM2

OSA


Platform

Nexus

Platform

Nexus

Platform

Nexus

Platform

Nexus

Platform

Nexus


Affymetrix Genome-Wide Human SNP array 6.0

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes


Agilent Human Genome CGH 244A

Yes

Yes

Yes

0n

Yes

Yes

Yes

Yes

Yes

Yes


Illumina HumanExon510s-duo

Yes

Yes

Yes

Yes

Yes

Yes

3n/4n

3n

Yes

Yes


Nimblegen HG18 CGH 385 k WG Tiling v1.01

-

1n

-

Yes

-

Yes

-

3n

-

Yes


1Nimblegen's analysis software segments the data without scoring of copy number

Detection of copy number of five specific chromosomes or chromosomal regions representing 0, 1, 3 and 4 copies in TC-32, as well as high-level amplification in OSA, using the platform-specific software and the platform-independent software Nexus.

Kresse et al. BMC Research Notes 2010 3:223   doi:10.1186/1756-0500-3-223

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