Table 1

Number of adverse drug reactions reported for psychotropic medication in the paediatric population by age and seriousness (in italic) (1998 to 2007)

Age groups (years)

<1

1<2

2-10

11<17

Total


Antipsychotics (N05A)

Levomepromazine

1 (1)

0

0

1

2 (1)

Zipradison

0

0

2

16 (11)

18 (11)

Zuclopenthixol

1 (1)

0

0

1 (1)

2 (2)

Chlorprothixene

0

0

0

2

2

Clozapine

0

0

0

1

1

Olanzapine

8 (8)

5 (5)

0

11 (3)

24 (16)

Quetiapine

1 (1)

0

1 (1)

14 (12)

16 (14)

Sulpiride

0

0

0

3

3

Risperidone

1 (1)

0

5

18 (5)

24 (6)

Aripiprazol

0

0

0

14 (3)

14 (3)

Total

12 (12)

5 (5)

8 (1)

81 (35)

106 (53)


Hypnotics and sedatives (N05B/N05C)

Diazepam

1 (1)

0

0

0

1 (1)

Oxazepam

3 (3)

0

0

0

3 (3)

Buspirone

1 (1)

0

0

0

1 (1)

Chloral hydrate

0

0

3 (3)

0

3 (3)

Midazolam

0

0

1 (1)

2 (2)

3 (3)

Total

5 (5)

0

4 (4)

2 (2)

11 (11)


Antidepressants (N06A)

Imipramine

0

0

1 (1)

0

1 (1)

Clomipramine

1 (1)

0

0

0

1 (1)

Amitriptyline

2 (2)

0

0

0

2 (2)

Fluoxetine

14 (14)

0

0

1 (1)

15 (15)

Citalopram

17 (17)

4 (4)

5 (2)

10 (6)

36 (29)

Paroxetine

5 (4)

0

0

6 (2)

11 (6)

Sertralin

11 (11)

0

9 (3)

25 (20)

45 (34)

Escitalopram

1 (1)

1 (1)

0

0

2 (2)

Oxitriptan

0

0

0

3

3

Mirtazapin

1 (1)

0

0

12 (8)

13 (9)

Venlafaxin

1 (1)

0

0

3

4 (1)

Total

53 (52)

5 (5)

15 (6)

60 (37)

133 (100)


Psychostimulants (N06B)

Methylphenidate

0

0

85 (35)

44 (17)

129 (52)

Modafinil

0

0

0

7 (7)

7 (7)

Atomoxetine

0

0

23 (7)

20 (11)

43 (18)

Total

0

0

108 (42)

71 (35)

179 (77)


Total N05 and N06

70 (69)

10 (10)

135 (53)

214 (109)

429 (241)


Aagaard and Hansen BMC Research Notes 2010 3:176   doi:10.1186/1756-0500-3-176

Open Data