Transcriptional and post-transcriptional regulation of DM loci genes. In panel A, transcriptional (x-axis) and post-transcriptional (y-axis) differential expression (DE, log fold change) related to the genes on the differentially methylated (DM) loci (average β differences, data points’ diameters. SULF2 only falls beyond the axes, indicating contribution of all 3 variations (transcriptional, post-transcriptional, methylation) to its final state. Panel B quantifies further such variations.
Lu et al. BMC Medical Genomics 2014 7:12 doi:10.1186/1755-8794-7-12