Workflow used for the prediction of the methylation status of CpG island in human genome. The CpG island map is obtained by applying the traditional Gardiner-Garden sequence criteria on non-repetitive sequences of the human genome. The core steps of our model development consist of three parts - feature extraction, feature selection and predictive modeling.
Zheng et al. BMC Medical Genomics 2013 6(Suppl 1):S13 doi:10.1186/1755-8794-6-S1-S13