Table 7

Ten most up-regulated pathways by insulin in the insulin-sensitive group

GO category

Pathway name

Nominal p

Permuted p


GO:0048534/GO:0002520

hemopoietic or lymphoid organ development/immune system development

1.43E-05

0.0004


GO:0016125

sterol metabolic process

1.94E-05

0.0005


GO:0006469

negative regulation of protein kinase activity

2.86E-05

0.0002


GO:0009725

response to hormone stimulus

3.06E-05

0.001


GO:0030684

Preribosome

3.95E-05

0.0002


GO:0051348

negative regulation of transferase activity

4.78E-05

0.0003


GO:0006629

lipid metabolic process

5.94E-05

0.0023


GO:0008203

cholesterol metabolic process

6.44E-05

0.001


GO:0009887

organ morphogenesis

7.59E-05

0.0029


GO:0030097

hemopoiesis

7.68E-05

0.0023


Soronen et al. BMC Medical Genomics 2012 5:9   doi:10.1186/1755-8794-5-9

Open Data