Table 4

Ten most down-regulated pathways in insulin-resistant compared to insulin-sensitive group after an overnight fast

GO category

Pathway name

Nominal p

Permuted p


GO:0032787

monocarboxylic acid metabolic process

5.6E-06

0.0001


GO:0055114

oxidation reduction

9.7E-06

0.0003


GO:0006066

cellular alcohol metabolic process

1.4E-05

0.0005


GO:0008131

amine oxidase activity

2.6E-05

0.0002


GO:0006631

fatty acid metabolic process

5.8E-05

0.0012


GO:0016638

oxidoreductase activity, acting on the CH-NH2 group of donors

1.0E-04

0.0003


GO:0006725

cellular aromatic compound metabolic process

1.2E-04

0.0022


GO:0006642

triacylglycerol mobilization

1.5E-04

0.0001


GO:0042594

response to starvation

2.1E-04

0.0012


GO:0016645

oxidoreductase activity, acting on the CH-NH group of donors

2.5E-04

0.002


Soronen et al. BMC Medical Genomics 2012 5:9   doi:10.1186/1755-8794-5-9

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