Intricate association between the expression of miR-146a and type 1 IFN signature score in a subclass of myositis. Data points are colored by the sample type in this scatter plot; color key is displayed in the upper right corner of the plot. The identity reference line y=x is denoted by the blue dotted line. Type 1 IFN signature displays a positive pattern of association in most subjects including the normal control, NM, PM, IBM and some DM, as highlighted in the light blue shaded oval. On the other hand, the type 1 IFN signature displays a negative pattern of association with the expression level of miR-146a in most DM (highlighted in the pink shaded oval). The subject identifiers of the eight DM subjects are all labeled in this plot.
Zhu et al. BMC Medical Genomics 2012 5:53 doi:10.1186/1755-8794-5-53