Open Access Research article

Genomic signatures characterize leukocyte infiltration in myositis muscles

Wei Zhu1*, Katie Streicher1, Nan Shen2, Brandon W Higgs1, Chris Morehouse1, Lydia Greenlees1, Anthony A Amato4, Koustubh Ranade1, Laura Richman1, David Fiorentino3, Bahija Jallal1, Steven A Greenberg45 and Yihong Yao1*

Author Affiliations

1 Translational Sciences, MedImmune, LLC, One MedImmune Way, Gaithersburg, MD, 20878, USA

2 Shanghai Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

3 Department of Dermatology, Stanford University School of Medicine, Palo Alto, CA, USA

4 Department of Neurology, Brigham and Women’s Hospital Harvard Medical School, Boston, MA, USA

5 Children’s Hospital Informatics Program, Harvard Medical School, Boston, MA, USA

For all author emails, please log on.

BMC Medical Genomics 2012, 5:53  doi:10.1186/1755-8794-5-53

Published: 21 November 2012

Additional files

Additional file 1:

Table S1. 837 differentially expressed transcripts in myositis compared to normal controls.

Format: XLS Size: 214KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Supplementary material. Supplementary information and figures for the main manuscript.

Format: DOC Size: 582KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 3:

Table S2. Numbers of the differentially expressed transcripts in the subclasses of myositis compared to normal controls.

Format: XLS Size: 27KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 4:

Table S3. 69 differentially expressed miRNAs in myositis compared to normal controls.

Format: XLS Size: 32KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 5:

Table S4. List of the gene members of the clusters A-E.

Format: XLS Size: 35KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 6:

Table S5. Overexpressed transcripts after adjustment with the leukocyte index.

Format: XLS Size: 27KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 7:

Table S6. Subclass-specific overexpressed transcripts after adjustment with the leukocyte index.

Format: XLS Size: 28KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 8:

Table S7. miRNA-target mRNA pair candidates.

Format: XLS Size: 34KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data