Table 3 |
||||
| Betweenness centrality of CCRG compared with random genes | ||||
| mean of CCRG | mean of random gene | fold** | p value# | |
| BIND | 98654.40138 | 23213.11683 | 4.24994 | <0.001 |
| IntAct | 149690.9051 | 36049.94851 | 4.15232 | 0.008 |
| MINT | 93562.07001 | 27842.49937 | 3.36058 | 0.015 |
| HPRD | 214315.4538 | 40236.19003 | 5.32644 | <0.001 |
| BioGRID | 281377.0414 | 51171.666 | 5.49869 | 0.01 |
| OPHID | 252315.597 | 39821.59949 | 6.33615 | <0.001 |
**fold is the result of mean betweenness centrality of CCRG divided by that of random genes.
#1000 random gene sets was selection from network, each randomization kept the number of selected genes same as that of real genes. Then for CCRG, p value was calculated over 1000 randomization.
Chen et al. BMC Medical Genomics 2012 5:43 doi:10.1186/1755-8794-5-43