Open Access Highly Accessed Research article

Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice

Wilma T Steegenga1*, Nicole JW de Wit12, Mark V Boekschoten12, Noortje IJssennagger12, Carolien Lute1, Shohreh Keshtkar1, Mechteld M Grootte Bromhaar12, Ellen Kampman1, Lisette C de Groot1 and Michael Muller12

Author Affiliations

1 Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands

2 The Netherlands Nutrigenomics Centre, TI Food and Nutrition, Wageningen, The Netherlands

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BMC Medical Genomics 2012, 5:38  doi:10.1186/1755-8794-5-38

Published: 28 August 2012

Additional files

Additional file 1:

Table S1. All genes differential expressed in one or more segments of the intestine in old mice fed a low-fat or high-fat diet.

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Additional file 2:

Table S2. Immune response and inflammatory genes regulated in old mice fed a low-fat or high-fat diet.

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Additional file 3:

Table S3. All genes differential expressed in one or more segments of the intestine in response to a high-fat diet.

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Additional file 4:

Table S4. Genes present in the IAP functional categories presented in Figure 5B regulated by a high-fat diet in the distal part of the small intestine in young and old mice.

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