Open Access Highly Accessed Research article

A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy

Robin M Hallett1, Gregory Pond2 and John A Hassell1,3*

1 Department of Biochemistry and Biomedical Sciences, Centre for Functional Genomics, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5, Canada

2 Department of Oncology, Juravinski Hospital and Cancer Centre, 711 Concession Street, Hamilton, Ontario, L8V 1C3, Canada

3 Centre for Functional Genomics, McMaster University, 1280 Main St West, Hamilton, Ontario, L8S 4K1, Canada

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BMC Medical Genomics 2012, 5:16 doi:10.1186/1755-8794-5-16

Published: 11 May 2012

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Additional file 1:

Table S1 and Table S2: Elements comprising the TOP2A and β-tubulin indices. Probe sets comprising the TOP2A and β-tubulin indices.

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Additional file 2:

Figure S1: The E2F1 index is predictive of chemotherapy response in multiple datasets A) GSE21094 (n = 278, TFAC). B) GSE25055 (n = 310, AT). C) GSE25065(n = 198,AT).

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