Additional file 12.

Top 5000 most variable genes (columns) on Colon cell lines (rows) sorted by PC1. PC1 is observed to be positively correlated to EMT signature score and anti-correlated to RAS signature score. Genes are clustered using Pearson correlation distance metric and Ward linkage. Heatmap shows mean-centered probe intensities.

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Loboda et al. BMC Medical Genomics 2011 4:9   doi:10.1186/1755-8794-4-9