Additional file 1.

Ingenuity/GO Analysis produced multiple functional categories for PC1 without bringing clarity to the underlying biology. The table lists top functional gene groups in terms of significance for enrichment of genes from PC1 signature. Both, significance of enrichment p-value,(based on hyper geometric distribution) and Bonferroni-type correction e-value (to account for multiple testing). Gene sets from Ingenuity, KEGG, and GeneGO were included in the analysis.

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Loboda et al. BMC Medical Genomics 2011 4:9   doi:10.1186/1755-8794-4-9