Table 6

Top most regulated genes after BMP7 signaling.

# regulated events

Gene Id

Gene name

Gene description

Up

Down

Total


ENSG00000109163

GNRHR

gonadotropin-releasing hormone receptor

19

0

19

ENSG00000157322

CLEC18A

C-type lectin domain family 18, member A

16

1

17

ENSG00000179088

C12orf42

Uncharacterized protein C12orf42

15

0

15

ENSG00000123329

ARHGAP9

Rho GTPase activating protein 9

14

0

14

ENSG00000144724

PTPRG

protein tyrosine phosphatase, receptor type, G

14

0

14

ENSG00000185630

PBX1

pre-B-cell leukemia homeobox 1

13

0

13

ENSG00000114850

SSR3

signal sequence receptor, gamma (translocon-associated protein gamma)

9

4

13

ENSG00000186153

WWOX

WW domain containing oxidoreductase

5

8

13

ENSG00000234906

APOC2

apolipoprotein C-II

12

0

12

ENSG00000180532

ZSCAN4

zinc finger and SCAN domain containing 4

12

0

12

ENSG00000144711

IQSEC1

IQ motif and Sec7 domain 1

12

0

12

ENSG00000138821

SLC39A8

solute carrier family 39 (zinc transporter), member 8

11

1

12

ENSG00000165995

CACNB2

calcium channel, voltage-dependent, beta 2 subunit

3

9

12

ENSG00000122859

NEUROG3

neurogenin 3

8

4

12

ENSG00000212128

TAS2R13

taste receptor, type 2, member 13

6

6

12

ENSG00000184999

SLC22A10

solute carrier family 22, member 10

11

0

11

ENSG00000183914

DNAH2

dynein, axonemal, heavy chain 2

11

0

11

ENSG00000125968

ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

11

0

11

ENSG00000167962

ZNF598

zinc finger protein 598

10

1

11

ENSG00000181722

ZBTB20

zinc finger and BTB domain containing 20

3

8

11

ENSG00000091482

SMPX

small muscle protein, X-linked

10

0

10

ENSG00000117318

ID3

inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

10

0

10

ENSG00000163694

RBM47

RNA binding motif protein 47

10

0

10

ENSG00000006007

GDE1

glycerophosphodiester phosphodiesterase 1

9

1

10

ENSG00000164104

HMGB2

high-mobility group box 2

8

2

10

ENSG00000250589

DUX4

double homeobox 4

2

8

10

ENSG00000130559

CAMSAP1

calmodulin regulated spectrin-associated protein 1

3

7

10

ENSG00000166501

PRKCB

protein kinase C, beta

4

6

10

ENSG00000186115

CYP4F2

cytochrome P450, family 4, subfamily F, polypeptide 2

4

6

10


Differentially expressed genes resulting from the general filtering of BMP7 data (905) were ranked according to the number of times a gene was up- and downregulated throughout the series of cell lines and time points. Only those genes with total rank value of at least 10 are listed.

Rodriguez-Martinez et al. BMC Medical Genomics 2011 4:80   doi:10.1186/1755-8794-4-80

Open Data