Open Access Research article

Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of genes

Alejandra Rodriguez-Martinez1, Emma-Leena Alarmo1, Lilli Saarinen2, Johanna Ketolainen1, Kari Nousiainen2, Sampsa Hautaniemi2 and Anne Kallioniemi1*

Author Affiliations

1 Laboratory of Cancer Genetics, Institute of Biomedical Technology, University of Tampere and Centre for Laboratory Medicine, Tampere University Hospital, Finland

2 Computational Systems Biology Laboratory, Genome-Scale Biology Research Program, Institute of Biomedicine, University of Helsinki, Finland

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BMC Medical Genomics 2011, 4:80  doi:10.1186/1755-8794-4-80

Published: 25 November 2011

Additional files

Additional file 1:

List of probes in group C. The expression values are represented as log2 ratios. Data was colored according to the accompanying color key. The data sheet contains 210 probes.

Format: XLS Size: 318KB Download file

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Additional file 2:

GO enrichment results for group C genes.

Format: XLS Size: 37KB Download file

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Additional file 3:

Model-based clustering results and GO enrichment. The probe clusters obtained are represented as well as the results of the GO enrichment analyses. GO terms are colored according to the accompanying color key.

Format: XLS Size: 1.9MB Download file

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Additional file 4:

Most commonly regulated genes with rank 6 or higher. The expression values are represented as log2 ratios. Data was colored according to the accompanying color key. The data sheets contain 608 and 281 genes for BMP4 and BMP7, respectively.

Format: XLS Size: 768KB Download file

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