Table 1

Clinicopathological details

Category

Patient characteristics

Biopsies (%)

Cell lines (%)

Xenografts (%)


Total nr of samples

76 (100)

13 (100)

18 (100)


Institution

LUMC, Netherlands

29 (38.2)

0 (0)

0 (0)


IOR, Italy

11 (14.5)

7 (53.8)

0 (0)


LOH, Sweden

3 (3.9)

0 (0)

0 (0)


Radiumhospitalet, Norway

1 (1.3)

3 (23.1)

12 (66.7)


UV, Spain

0 (0)

0 (0)

6 (33.3)


WWUM, Germany

32 (42.1)

0 (0)

0 (0)


Other

0 (0)

3 (23.1)

0 (0)


Origin

Biopsy

76 (100)

0 (0)

0 (0)


Resection

0 (0)

7 (53.8)

11 (61.1)


Metastasis

0 (0)

3 (23.1)

1 (5.6)


Unknown

0 (0)

3 (23.1)

6 (33.3)


Location of primary tumor

Femur

36 (47.4)

0 (0)

10 (55.6)


Tibia/fibula

26 (34.2)

0 (0)

2 (11.1)


Humerus

10 (13.2)

0 (0)

2 (11.1)


Axial skeleton

1 (1.3)

0 (0)

1 (5.6)


Unknown/other

3 (3.9)

13 (100)

3 (16.7)


Histological subtype

Osteoblastic

50 (65.8)

9 (69.2)

15 (83.3)


Chondroblastic

9 (11.8)

0 (0)

3 (16.7)


Fibroblastic

7 (9.2)

4 (30.8)

0 (0)


Minor

10 (13.2)

0 (0)

0 (0)


Histological response to pre-operative chemotherapy in the primary tumor

Good response

33 (43.4)

0 (0)

0 (0)


Poor response

36 (47.4)

0 (0)

0 (0)


Unknown/NA

7 (9.2)

13 (100)

18 (100)


Sex

Male

52 (68.4)

9 (69.2)

9 (50)


Female

24 (31.6)

4 (30.8)

3 (16.7)


Unknown

0 (0)

0 (0)

6 (33.3)


Clinicopathological details of patients with conventional high-grade osteosarcoma, including all patients from the biopsy, cell line, and xenograft datasets.

Kuijjer et al. BMC Medical Genomics 2011 4:66   doi:10.1186/1755-8794-4-66

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