Open Access Highly Accessed Research article

Identification of candidate genes linking systemic inflammation to atherosclerosis; results of a human in vivo LPS infusion study

Suthesh Sivapalaratnam1*, Rosienne Farrugia2, Max Nieuwdorp1, Cordelia F Langford3, Rachel T van Beem4, Stephanie Maiwald1, Jaap Jan Zwaginga4, Arief Gusnanto5, Nicholas A Watkins26, Mieke D Trip1 and Willem H Ouwehand236

Author Affiliations

1 Department of Vascular Medicine, Academic Medical Center, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands

2 Department of Hematology, University of Cambridge, Long Road, CB2 0PT, Cambridge, UK

3 Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, Cambridge, UK

4 Department of Experimental Immunohematology, Sanquin Research, Plesmanlaan 125, 1066 CX, Amsterdam, The Netherlands

5 Department of Statistics, University of Leeds, Woodhouse lane, LS2 9JT, Leeds, UK

6 National Health Service Blood and Transplant, Cambridge, Long Road, CB2 0PT, UK

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BMC Medical Genomics 2011, 4:64  doi:10.1186/1755-8794-4-64

Published: 10 August 2011

Additional files

Additional file 1:

Supplementary Methods. Full methods of the in vitro experiments.

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Additional file 2:

LPS Supplementary Table 1. RNA yield and quality data for all samples and those included in the study.

Format: DOC Size: 43KB Download file

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Additional file 3:

LPS Supplementary Table 2. cDNA quantity, quality, labeling and amplification data for all samples and those included in the study.

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Additional file 4:

Supplementary Table 3 Ctrl vs LPS in vitro. Full results of the in vitro experiments.

Format: XLS Size: 215KB Download file

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