Identification of transcriptional regulatory networks specific to pilocytic astrocytoma
1 Department of Pathology and Immunology, Washington University School of Medicine, 660. S. Euclid Ave. St. Louis, MO, 63110, USA
2 Department of Pediatrics, Emory University, Atlanta, GA, 30322, USA
3 Department of Neurology, Washington University School of Medicine, 660. S. Euclid Ave. St. Louis, MO, 63110, USA
BMC Medical Genomics 2011, 4:57 doi:10.1186/1755-8794-4-57Published: 11 July 2011
Additional file 1:
The 792 gene set that is differentially expressed in PAs along with each gene's expression differences when compared to the control are shown.
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Additional file 2:
PA network obtained as a result of step 3 in Figure 2. Transcription factors (TF) are shown by large solid circles, target genes are shown by small solid circles. Interactions between TF-TF and TF-target are shown by directed edges. Genes overexpressed in PA relative to non-malignant brain tissue are shown in red while genes whose expression is lower in PA are shown in green.
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