Table 3

Datasets in which genes in common metastatic signature of metastasis are significant with a Q < 0.1

Genes differentially

expressed in metastasis

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

Num studies


Up - regulated genes

EZH2

X

X

X

X

X

5

Down - regulated genes

ACTG2

X

X

X

X

4

FUCA1

X

X

X

X

4

JUNB

X

X

X

X

4

PDE4D

X

X

X

X

4

RAP1A

X

X

X

X

4

SYNPO2

X

X

X

X

4

CASP7

X

X

X

X

4

GADD45B

X

X

X

X

4

KRT15

X

X

X

X

4

PIGB

X

X

X

X

4

RARRES1

X

X

X

X

4

TCF21

X

X

X

X

4

CSRP1

X

X

X

X

4

GJA1

X

X

X

X

4

LUM

X

X

X

X

4

PKIG

X

X

X

X

4

SELE

X

X

X

X

4

TMEM49

X

X

X

X

4

CYR61

X

X

X

X

4

GNG12

X

X

X

X

4

MAPK1

X

X

X

X

4

PLA2G2A

X

X

X

X

4

SLC12A4

X

X

X

X

4

TPM1

X

X

X

X

4

DPT

X

X

X

X

4

GSN

X

X

X

X

4

MFAP4

X

X

X

X

4

PLEKHC1

X

X

X

X

4

SMTN

X

X

X

X

4

TSC22D1

X

X

X

X

4

DSTN

X

X

X

X

4

IER2

X

X

X

X

4

NBL1

X

X

X

X

4

PPP1R12A

X

X

X

X

4

SORBS1

X

X

X

X

4

VCL

X

X

X

X

4

FILIP1L

X

X

X

X

4

ISL1

X

X

X

X

4

PAGE4

X

X

X

X

4

FLNC

X

X

X

X

4

JMJD3

X

X

X

X

4

PAM

X

X

X

X

4

FOSB

X

X

X

X

4

PCP4

X

X

X

X

4

ACTA2

X

X

X

X

X

5

CNN1

X

X

X

X

X

5

DMN

X

X

X

X

X

5

HBEGF

X

X

X

X

X

5

MGP

X

X

X

X

X

5

PYRO1D1

X

X

X

X

X

5

TACC1

X

X

X

X

X

5

BMPR1A

X

X

X

X

X

5

CTGF

X

X

X

X

X

5

FBLN1

X

X

X

X

X

5

KCNMA1

X

X

X

X

X

5

NR4A1

X

X

X

X

X

5

RBPMS

X

X

X

X

X

5

TAGLN

X

X

X

X

X

5

CAMK2G

X

X

X

X

X

5

DIO2

X

X

X

X

X

5

FHL1

X

X

X

X

X

5

LMOD1

X

X

X

X

X

5

NR4A3

X

X

X

X

X

5

SPARCL1

X

X

X

X

X

5

ZFP36

X

X

X

X

X

5

CCND2

X

X

X

X

X

5

DKFZP564O0823

X

X

X

X

X

5

FXYD3

X

X

X

X

X

5

MCL1

X

X

X

X

X

5

PPP1R12B

X

X

X

X

X

5

SPG20

X

X

X

X

X

5

BTG2

X

X

X

X

X

X

6

JUND

X

X

X

X

X

X

6

KCNMB1

X

X

X

X

X

X

6

MYH11

X

X

X

X

X

X

6

MYLK

X

X

X

X

X

X

6

SOD3

X

X

X

X

X

X

6

TPM2

X

X

X

X

X

X

X

X

8


The studies in which each gene is differentially expressed are given as an × under the study number, as given in Table 1. "Num studies" refers to the total number of studies in which the gene is significantly differentially expressed with a Q-value < 0.1.

Daves et al. BMC Medical Genomics 2011 4:56   doi:10.1186/1755-8794-4-56

Open Data