Table 9

Gene Ontology categories enriched among the genes associated with lifetime glioblastoma survival1

Gene Ontology

Level

Term

P-value

FDR adjusted P-value

Number of genes

Genes


Biological process

3

aging (GO:0007568)

2.13E-05

1.62E-03

3

Pdcd4, Cdkn2a, Tp53

regulation of biological process (GO:0050789)

2.77E-04

1.50E-02

20

Usf2, Cdkn2a, Ccnb2, Akt2, Tp53, Cdc42, Six6, Jag2, Lin7c, Pdcd4, Csf1, Topors, Spg21, Akt1, Egfr, Sox10, C2, Scn5a, Arhgef4, Cdk2

protein localization (GO:0008104)

1.49E-03

3.77E-02

7

Topors, Akt1, Sar1a, Egfr, Timm23, Tp53, Lin7c

cell division (GO:0051301)

2.04E-03

3.88E-02

3

Ccnb2, Cdc42, Cdk2

cell cycle (GO:0007049)

3.75E-03

5.14E-02

7

Pdcd4, Egfr, Cdk2, Cdkn2a, Ccnb2, Tp53, Jag2

nitrogen compound metabolic process (GO:0006807)

4.06E-03

5.14E-02

4

Chst4, Akt1, Egfr, Chi3l1

cell proliferation (GO:0008283)

8.32E-03

8.99E-02

6

Csf1, Topors, Egfr, Cdk2, Tp53, Jag2

death (GO:0016265)

9.46E-03

8.99E-02

6

Akt1, Cdkn2a, Tp53, Jag2, Pdcd4, Topors


4

cell aging (GO:0007569)

4.38E-06

9.42E-04

3

Pdcd4, Cdkn2a, Tp53


1 Only GO categories with False Discovery Rate (FDR) adjusted P-value < 0.1 and represented by three or more genes.

SerĂ£o et al. BMC Medical Genomics 2011 4:49   doi:10.1186/1755-8794-4-49

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