Table 8

Genes that have a cohort-dependent association (P-value < 0.05) with progression-free glioblastoma survival

Gene Symbol

Probe Identifier

Clinical Cohort

P-value

Level of Clinical Cohort

Hazard Ratio1

Relevant literature references


Gdf10

206159_at

Gender

0.0317

Male

0.37 (0.23-0.60)

n/a

Female

0.80 (0.45-1.42)

Vav3

218807_at

Race

0.008

Other

0.41 (0.29-0.59)

[81]G

White

0.68 (0.55-0.85)

Rps20

216246_at

Race

0.0003

Other

0.75 (0.39-1.44)

[75]O

White

1.83 (1.03-3.24)

Rab31

217764_s_at

Race

<.0001

White

1.47 (0.93-2.30)

[74]O

Other

7.72 (3.71-16.07)

Apool

213289_at

Therapy

0.0026

R

1.64 (1.13-2.38)

[131]O

None

1.93 (0.63-5.98)

CRnoT

2.23 (1.55-3.20)

Other

3.86 (1.83-8.13)

CRT

4.82 (2.69-8.63)


n/a, No association with any type of cancer found in literature;

1 Hazard ratio estimate (95% confidence interval);

G Gene confirmed in an independent glioblastoma multiforme study; the number between square brackets denotes the corresponding literature reference

O Gene confirmed in an independent study on any other type of cancer; the number between square brackets denotes the corresponding literature reference.

SerĂ£o et al. BMC Medical Genomics 2011 4:49   doi:10.1186/1755-8794-4-49

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