Table 6

Genes that have a cohort-dependent association (P-value < 0.05) with the overall glioblastoma survival

Gene Symbol

Probe Identifier

Clinical Cohort

P-value

Level of Clinical Cohort

Hazard Ratio1

Relevant literature references


Polr2d

214144_at

Therapy

0.0044

Other

0.35 (0.18-0.70)

[117]O

R

0.50 (0.31-0.81)

CRT

0.68 (0.38-1.21)

None

0.77 (0.43-1.39)

CRnoT

0.93 (0.58-1.5)

Igf2bp3

203820_s_at

Gender

0.0146

Female

1.02 (0.84-1.24)

[118]O

Male

1.29 (1.12-1.49)


n/a, No association with any type of cancer found in literature;

1 Hazard ratio estimate (95% confidence interval);

G Gene confirmed in an independent glioblastoma multiforme study; the number between square brackets denotes the corresponding literature reference;

O Gene confirmed in an independent study on any other type of cancer; the number between square brackets denotes the corresponding literature reference.

SerĂ£o et al. BMC Medical Genomics 2011 4:49   doi:10.1186/1755-8794-4-49

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