Open Access Research article

Genome-wide joint SNP and CNV analysis of aortic root diameter in African Americans: the HyperGEN study

Nathan E Wineinger1*, Amit Patki1, Kristin J Meyers2, Ulrich Broeckel3, Charles C Gu4, DC Rao4, Richard B Devereux5, Donna K Arnett6 and Hemant K Tiwari1

Author Affiliations

1 Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA

2 Department of Population Health Sciences, University of Wisconsin-Madison, Madison, WI, USA

3 Department of Pediatrics, Medical College of Wisconsin, Milwaulkee, WI, USA

4 Division of Biostatistics, Washington University, St. Louis, MO, USA

5 Division of Cardiology, Weill Cornell Medical College, New York, NY, USA

6 Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA

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BMC Medical Genomics 2011, 4:4  doi:10.1186/1755-8794-4-4

Published: 11 January 2011

Additional files

Additional file 1:

S1. SNP quality control and principal component analysis.

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Additional file 2:

Table S1. Eigenvalues of the top 30 principal components.

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Additional file 3:

Table S2. Top 1,000 results from the second stage of the analysis.

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Additional file 4:

Figure S1. Quantile-quantile plot of genome-wide results from the first stage (GRAMMAR) procedure.

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