Open Access Research article

Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study

Marit Waaseth1*, Karina S Olsen1, Charlotta Rylander12, Eiliv Lund1 and Vanessa Dumeaux1

Author Affiliations

1 Department of Community Medicine, University of Tromsø, Tromsø, Norway

2 Norwegian Institute for Air Research, Tromsø, Norway

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BMC Medical Genomics 2011, 4:29  doi:10.1186/1755-8794-4-29

Published: 31 March 2011

Additional files

Additional file 1:

Questionnaire, translated from Norwegian. This is a PDF-file of the questionnaire that the women completed at the time of the blood draw.

Format: PDF Size: 60KB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 2:

Gene sets included in the gene set enrichment analysis. This is a Word table showing all the 56 gene sets included in the analysis. The gene sets are categorised as related to female sex hormone or menopause, as related to blood cells and the immune system, or, as related to other factors.

Format: DOC Size: 168KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional file 3:

Gene sets differentially expressed between high and low hormone concentrations, age adjusted with HT and thyroxin users excluded. This is a Word table showing which of the 56 gene sets that showed a statistically significant differential expression between the women with high and low plasma concentrations of estradiol and progesterone.

Format: DOC Size: 188KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data