Open Access Highly Accessed Research article

Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples

Serban Nacu, Wenlin Yuan, Zhengyan Kan, Deepali Bhatt, Celina Sanchez Rivers, Jeremy Stinson, Brock A Peters, Zora Modrusan, Kenneth Jung, Somasekar Seshagiri* and Thomas D Wu*

Author Affiliations

Departments of Bioinformatics and Molecular Biology, Genentech, Inc., South San Francisco, California 94080, USA

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BMC Medical Genomics 2011, 4:11  doi:10.1186/1755-8794-4-11

Published: 24 January 2011

Additional files

Additional file 1:

TIC events found by targeted detection approach.

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Additional file 2:

Supporting reads for TIC events.

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Additional file 3:

TICs with intervening exons.

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Additional file 4:

Distant fusions found by spliced alignment approach.

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Additional file 5:

Supporting reads for distant fusions.

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Additional file 6:

Sample information and pathology evaluation.

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Additional file 7:

Primers and probes used for qRT-PCR measurements.

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