Table 6

Top-ranked methylation sites in MAF signature in the TCGA ovarian cancer data set

Methylation site

MI

Hyper-/Hypomethylated


PRAME

0.223

Hyper

SNAI1

0.183

Hyper

KRT7

0.158

Hyper

RASSF5

0.157

Hyper

FLJ14816

0.155

Hyper

PPL

0.155

Hyper

CXCR6

0.153

Hypo

SLC12A8

0.148

Hyper

NFATC2

0.148

Hyper

HOM-TES-103

0.147

Hypo

ZNF556

0.147

Hyper

OCIAD2

0.146

Hyper

APS

0.142

Hyper

MGC9712

0.139

Hyper

SLC1A2

0.136

Hyper

HAK

0.131

Hypo

C3orf18

0.13

Hyper

GMPR

0.13

Hyper

CORO6

0.128

Hyper


All methylated genes have multiple-test corrected p < 10-16 in terms of their association with COL11A1.

Kim et al. BMC Medical Genomics 2010 3:51   doi:10.1186/1755-8794-3-51

Open Data