Open Access Highly Accessed Research article

Gene regulatory network reveals oxidative stress as the underlying molecular mechanism of type 2 diabetes and hypertension

Jesmin1*, Mahbubur SM Rashid1, Hasan Jamil2, Raquel Hontecillas3 and Josep Bassaganya-Riera3

Author Affiliations

1 Department of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka-1000, Bangladesh

2 Department of Computer Science, Wayne State University, Michigan, USA

3 Nutritional Immunology and Molecular Nutrition Laboratory, Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA

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BMC Medical Genomics 2010, 3:45  doi:10.1186/1755-8794-3-45

Published: 13 October 2010

Additional files

Additional file 1:

Statistics of the reported genes associated with T2D, HT, OBS and ROS.

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Additional file 2:

Complete 'text-mined' data set.

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Additional file 3:

Predicted integrated network model of the four diseases (using Cytoscape).

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Additional file 4:

Gene annotation using GO, Genopedia and Phenopedia.

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