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Open Access Research article

Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks

Fabio Coppedè1*, Enzo Grossi23, Francesca Migheli1 and Lucia Migliore1

Author Affiliations

1 Department of Human and Environmental Sciences, Section of Medical Genetics, University of Pisa, Italy

2 Bracco Medical Department, San Donato Milanese, Italy

3 Semeion Research Centre, Rome, Italy

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BMC Medical Genomics 2010, 3:42  doi:10.1186/1755-8794-3-42

Published: 24 September 2010

Additional files

Additional file 1:

Database. The database used for analysis in an Excel .csv format.

Format: CSV Size: 3KB Download file

Open Data

Additional file 2:

Twist System. The pdf file contains a detailed description of the Twist system. This document already existed as documentation [22,24,25] and is included for clarity.

Format: PDF Size: 29KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

Auto-CM System. The pfd file contains a detailed description of the theory behind Auto-CM system. This document already existed as documentation [26,27] and is included for clarity.

Format: PDF Size: 34KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data