Oxidative stress of EPCs. A) Bar graph representation of C11-BO oxidation at different times (0, 1 and 6 hours) in DS and euploid EPCs in presence of hydroperoxide (200 ìM). Upper panel, C11-BO oxidation in hydroperoxide-treated euploid EPCs compared to DS (*P < 0.01). Lower panel, Bartonella-infected euploid and DS progenitors treated and untreated with hydroperoxide (*P < 0.01). B) SOD1 and S100B gene expression in euploid and DS EPCs by qRT-PCR. Data are shown as relative expression levels (Euploid EPC expression = 1).
Costa et al. BMC Medical Genomics 2010 3:40 doi:10.1186/1755-8794-3-40