Open Access Highly Accessed Research article

Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma

Jill C Rubinstein1, Nam Tran2, Shuangge Ma3, Ruth Halaban4 and Michael Krauthammer12*

Author Affiliations

1 Interdepartmental Program in Computational Biology & Bioinformatics, Yale University, New Haven, CT 06520, USA

2 Department of Pathology, Yale University, New Haven, CT 06520, USA

3 School of Public Health, Yale University, New Haven, CT 06520, USA

4 Department of Dermatology, Yale University, New Haven, CT 06520, USA

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BMC Medical Genomics 2010, 3:4  doi:10.1186/1755-8794-3-4

Published: 9 February 2010

Additional files

Additional file 1:

Genes identifiers. The file GenesByBin.txt contains refseq ID, name of the cell line, and class assignment (up-regulation by Decitabine) for each gene analyzed in the study. The file is organized by promoter category as defined in the text. The file also contains identifiers for the MCF-7 genes included in the analysis.

Format: TXT Size: 3.4MB Download file

Open Data