Open Access Highly Accessed Research article

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

Christopher G Bell1*, Andrew E Teschendorff1, Vardhman K Rakyan2, Alexander P Maxwell3, Stephan Beck1 and David A Savage3*

Author Affiliations

1 Medical Genomics, UCL Cancer Institute, University College London, London, UK

2 Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK

3 Nephrology Research Group, Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland, UK

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BMC Medical Genomics 2010, 3:33  doi:10.1186/1755-8794-3-33

Published: 5 August 2010

Additional files

Additional file 1:

Supplementary Figure S1. Distribution of CpG sites on Infinium platform. (Top, Left) Chromosome Distribution of CpG sites. (Top, Right) Distance to Transcription Start Site of CpG Locus. (Bottom, Left) Interrogated CpG Islands: near genes, near miRNA. (Bottom, Right) Number of CpG sites per CpG Island.

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Additional file 2:

Supplementary Table S1. List of CpGs with q value < 0.15. Column headings are IlmnID = Illumina CpG ID, Gene_ID = Entrez Gene ID, Symbol = Gene Symbol, coef = coefficient, exp(coef) = exponential of coefficient, se(coef) = standard error of coefficient, z = z score, Pr(> |z|) = probability greater than absolute z score, q value

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