Table 1

The most highly significant functional assignments for the set of smoking correlated genes

Function Annotation

P-value

Number of genes


Cell cytotoxicity

3.7 × 10-10

17

Proliferation of cells

2.1 × 10-9

65

Activation of cells

1.7 × 10-8

31

Cell movement

2.9 × 10-8

35

Lysis of cells

1.2 × 10-7

11

Immune response

2.2 × 10-7

38

Mobilization of calcium

4.0 × 10-7

19

Adhesion of cells

7.8 × 10-7

29

Cell death

1.1 × 10-6

66

Tumorigenesis

1.2 × 10-6

72

Binding of cells

2.9 × 10-6

21

Viral elimination

4.3 × 10-6

3

Cancer

4.9 × 10-6

64

Inflammatory disorder

5.3 × 10-6

44

Cell growth

5.6 × 10-6

50

Cardiovascular disorder of lung

1.4 × 10-4

3

Perturbation of mitochondria

2.7 × 10-4

2

Inflammatory response

3.4 × 10-4

18

Asthma

2.5 × 10-3

9

Free radical scavenging

3.1 × 10-3

8


Charlesworth et al. BMC Medical Genomics 2010 3:29   doi:10.1186/1755-8794-3-29

Open Data