Open Access Highly Accessed Research article

Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes

Jac C Charlesworth12*, Joanne E Curran1, Matthew P Johnson1, Harald HH Göring1, Thomas D Dyer1, Vincent P Diego1, Jack W Kent1, Michael C Mahaney1, Laura Almasy1, Jean W MacCluer1, Eric K Moses1 and John Blangero1

Author Affiliations

1 Department of Genetics, Southwest Foundation for Biomedical Research, P.O. Box 760549, San Antonio, TX, USA

2 Menzies Research Institute, Private Bag 23, Hobart, TAS, Australia

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BMC Medical Genomics 2010, 3:29  doi:10.1186/1755-8794-3-29

Published: 15 July 2010

Additional files

Additional file 1:

Full details of the smoking-correlated genes significant at an FDR of 0.05. Includes gene information, correlation of expression with smoking and the allocation of each gene into the functional assignments and canonical pathways from Ingenuity Pathways Analysis described in Tables 1 and 2.

Format: XLS Size: 142KB Download file

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Additional file 2:

Bivariate analysis results for the fifty most significant smoking-correlated transcripts. *Indicates there were multiple significant transcripts for this gene.

Format: XLS Size: 32KB Download file

This file can be viewed with: Microsoft Excel Viewer

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