Table 4

Summary of multipoint linkage signals in African American pedigrees.

Significance Criteria

Chr

Map position

Marker

Factor


P < 0.00002

5

71.143

D5S628

4B(POST):ADP

5

80.82

D5S2072

4B(POST):ADP


P < 0.00074

1

160.45

D1S484

2B(PRE):Collagen

1

216.774

D1S245

4B(POST):ADP

1

217.215

D1S205

4B(POST):ADP

2

78.417

D2S2156

5B(POST):ADP PRP

5

83.18814

D5S1967

4B(POST):ADP

8

69.341

D8S1737

4B(POST):ADP

11

154.04129

D11S969

4B(POST):ADP

17

102.596

D17S940

5B(PP): ADP

18

21.744

D18S967

7B(POST): ADP/Epinephrine

19

99.84163

D19S572

4B(PRE):Collagen Lag


POST = Post-ASA Factor, PRE = Pre-ASA Factor, PP = Post-adjusted-for-pre-ASA Factor, Chr = chromosome

Significance criteria as defined by Lander and Kruglyak (1995): suggestive linkage (p-value < 7 × 10-4) and significant linkage (p-value < 2 × 10-5).

Mathias et al. BMC Medical Genomics 2010 3:22   doi:10.1186/1755-8794-3-22

Open Data