Table 3

Summary of multipoint linkage signals in European American pedigrees.

Significance Criteria

Chr

Map Position

Marker

Factor


P < 0.00002

-

-

-


P < 0.00074

3

89.04039

D3S1600

2W(POST):Epinephrine

4

62.104

D4S405

3W(POST):High Dose Collagen/TXM

4

67.63

D4S396

3W(POST):High Dose Collagen/TXM

4

71.03

D4S428

3W(POST):High Dose Collagen/TXM

5

203.456

D5S469

5W(PP):ADP

6

174.4557

D6S1581

3W(PP):Collagen/TXM

11

126.83

D11S4089

2W(POST):Epinephrine

15

43.142

D15S146

7W(PP):High Dose ADP

15

52.712

D15S1016

7W(PP):High Dose ADP


POST = Post-ASA Factor, PRE = Pre-ASA Factor, PP = Post-adjusted-for-pre-ASA Factor, Chr = chromosome

Significance criteria as defined by Lander and Kruglyak (1995): suggestive linkage (p-value < 7 × 10-4) and significant linkage (p-value < 2 × 10-5).

Mathias et al. BMC Medical Genomics 2010 3:22   doi:10.1186/1755-8794-3-22

Open Data