Table 1 |
||||
|
Sequence variants identified in ASMT, MTNR1A, MTNR1B in patients with ASD. |
||||
|
Gene |
Location/ nucleotide change |
Amino acid change |
Cases (n = 109) |
Controls (n = 188) |
|
|
||||
|
ASMT |
c.-376G>A |
- |
1 |
1 |
|
|
||||
|
ASMT |
c.-38C>T |
- |
1 |
0 |
|
|
||||
|
ASMT |
IVS5+2T>C |
- |
1 |
0 |
|
|
||||
|
MTNR1A |
c.-158C>T |
- |
1 |
0 |
|
|
||||
|
MTNR1B |
c.370G>A |
V124I* |
1 |
0 |
|
|
||||
|
MTNR1B |
c.-39GC>AA |
- |
1 |
0 |
|
|
||||
|
* Predicted not to have any major effect on protein function, as assessed by Polyphen and SIFT. |
||||
|
Jonsson et al. BMC Medical Genomics 2010 3:10 doi:10.1186/1755-8794-3-10 |
||||
