Table 8

The QPCR results showed a significant decrease in brain gene expression of GLS in subjects with schizophrenia compared to controls.

Genes

BPD

FC

MDD

FC

SZ

FC

BPD versus C p-value

MDD versus C p-value

SZ versus C p-value


PDE4D

1.08

1.00

0.96

0.42

0.99

0.61


GLS

0.99

0.99

0.73

0.94

0.92

0.04


DSC2

0.99

1.06

0.97

0.93

0.40

0.66


DSC3

0.96

1.00

1.01

0.75

0.98

0.94


ADCY1

0.88

0.87

1.00

0.03

0.00

0.95


No significant alterations of DLPFC gene expression in schizophrenia of any other transcript examined. BPD -- bipolar disorder; C -- control; MDD --major depressive disorder; SZ -- schizophrenia; FC -- Fold Change

Martin et al. BMC Medical Genomics 2009 2:62   doi:10.1186/1755-8794-2-62

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