BMC Medical Genomics

official impact factor 3.77

Open Access Research article

Gene expression profile analysis of human hepatocellular carcinoma using SAGE and LongSAGE

Hui Dong1,2,5, Xijin Ge3, Yan Shen4, Linlei Chen6, Yalin Kong7, Hongyi Zhang7, Xiaobo Man2, Liang Tang2, Hong Yuan6, Hongyang Wang2, Guoping Zhao1,4,5* and Weirong Jin4,5*

Author Affiliations

1 Department of Microbiology and Microbial Engineering, School of Life Sciences, Fudan University, Shanghai 200433, PR China

2 International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University, Shanghai 200438, PR China

3 Department of Mathematics and Statistics, South Dakota State University, Brookings, SD 57006, USA

4 National Engineering Center for Biochip at Shanghai, Shanghai 201203, PR China

5 Chinese National Human Genome Center at Shanghai, 351 Guo Shou-Jing Road, Shanghai 201203, PR China

6 Center for Clinical Pharmacology, Third Xiangya Hospital, Central South University, Changsha 410013, PR China

7 Department of Hepatobiliary Surgery, General Hospital of Air Force PLA, Beijing 100036, PR China

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BMC Medical Genomics 2009, 2:5 doi:10.1186/1755-8794-2-5

Published: 26 January 2009

Additional files

Additional file 1:

List of genes differentially expressed in HCC vs normal liver. 224 genes were identified to be differentially expressed in HCC vs normal liver, with the significance p < 0.05 and fold change > 3.

Format: XLS Size: 67KB Download file

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Additional file 2:

Functional classification of genes up-regulated in HCC. 104 genes up-regulated in HCC were grouped into eight functional clusters and one unclassified cluster.

Format: XLS Size: 38KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

Functional classification of genes down-regulated in HCC. 120 genes down-regulated in HCC were assembled into seven functional clusters and one unclassified cluster.

Format: XLS Size: 39KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data