Table 4

Gene Ontology (GO) Annotation of genes analyzed in GeNorm

Gene Symbol

Gene Name

GO Biological Process Term

GO Molecular Function Term

GO Cellular Component

Term


FPGS

folylpolyglutamate synthase

nucleobase, nucleoside,

nucleotide and nucleic acid

metabolic process

glycine metabolic process

one-carbon compound metabolic

process

biosynthetic process

nucleoside metabolic

process

folic acid and derivative

biosynthetic process

nucleotide binding

Tetrahydrofolylpoly-

glutamate-synthase activity

ATP binding

ligase activity

cytoplasm

mitochondrion

cytosol


TRAP1

TNF receptor-associated protein 1

protein folding

nucleotide binding

receptor activity

tumor necrosis factor

receptor binding

ATP binding

unfolded protein binding

Mitochondrion


DECR1

2,4-dienoyl CoA reductase 1, mitochondrial

metabolic process

oxidation reduction

catalytic activity

Binding

2,4-dienoyl-CoA

reductase(NADPH)

activity

oxidoreductase activity

mitochondrion


PPIB

peptidylprolyl isomerase B (cyclophilin B)

protein folding

peptidyl-prolyl cis-trans

isomerase activity

protein binding

isomerase activity

peptide binding

unfolded protein binding

endoplasmic reticulum

endoplasmic reticulum

lumen

melanosome


HMBS

hydroxymethyl-bilane synthase

porphyrin biosynthetic process

heme biosynthetic process

tetrapyrrole biosynthetic process

hydroxymethylbilane synthase activity

transferase activity

cytoplasm


B2M

beta-2-microglobulin

antigen processing and presentation of peptide antigen via MHC class I

immune response

protein binding

Golgi membrane

extracellular region

plasma membrane

early endosome

membrane

MHC class I protein complex


Stamova et al. BMC Medical Genomics 2009 2:49   doi:10.1186/1755-8794-2-49

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