BMC Medical Genomics

official impact factor 3.77
Search for
Advanced search
BMC Medical Genomics
Tools
Share this article
Open Access Highly Access Research article

Detailed transcriptome atlas of the pancreatic beta cell

Burak Kutlu1*, David Burdick1, David Baxter1, Joanne Rasschaert2, Daisy Flamez2, Decio L Eizirik2, Nils Welsh3, Nathan Goodman1 and Leroy Hood1

Author Affiliations

1 Institute for Systems Biology, Seattle, WA, USA

2 Laboratory of Experimental Medicine, Universite Libre de Bruxelles, Brussels, Belgium

3 Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden

For all author emails, please log on.

BMC Medical Genomics 2009, 2:3 doi:10.1186/1755-8794-2-3

Published: 15 January 2009

Additional files

Additional file 1:

Supplementary methods. Supplementary information about Methods and additional findings.

Format: PDF Size: 258KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 2:

MPSS gene expression data. Tpm values for each gene in MPSS data.

Format: PDF Size: 435KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 3:

GO term enrichment analysis of MPSS data. GO term enrichment analysis of 1: top 200 genes, 2: genes expressed lower than 25 transcripts per million (tpm) in the human islet MPSS data

Format: XLS Size: 25KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 4:

Transcription factor analysis. Analysis of transcription factors in rat INS cell data based on domain classification.

Format: XLS Size: 171KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 5:

INS-1 cell microarray data analysis results. This file contains 1. MAS5-normalized expression data of rat β, α and INS cell. 2. Differential expression analysis of genes expressed in β vs α cells. 3. Differential expression analysis of genes expressed in β vs INS cells.

Format: PDF Size: 1.8MB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional file 6:

GO term enrichment analysis of INS cell data. GO term enrichment analysis genes expressed in β, α and INS cells.

Format: XLS Size: 43KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 7:

Pancreatic islet-specific genes. Genes that are enriched in pancreatic islets compared to other tissues in the body.

Format: XLS Size: 366KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 8:

The overlap of these pancreatic islet-specific genes with β and α cell enriched genes. The intersection of genes in Additional File 7 with either genes expressed strongly in either β or α cells.

Format: XLS Size: 88KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data