Table 3

Myelination related genes showing expression changes during adolescence

Gene

Symbol

Correlation with 15–25 template

Change in SZ

Number of studies


r

Adjusted p-value


Claudin 11

CLDN11

0.42

0.0613

Down

3 (2,4,6)

2',3'-cyclic nucleotide 3' phosphodiesterase

CNP

0.49

0.0258

Down

4 (2,3,4)

myelin associated glycoprotein

MAG

0.44

0.0496

Down

4 (1,2,3,4)

mal, T-cell differentiation protein

MAL

0.44

0.0471

Down

3 (1,3,5)

myelin basic protein

MBP

0.51

0.0201

Down

2 (5,6)

Myelin-associated oligodendrocytic basic protein

MOBP

0.35

0.1384

Down

2 (5,6)

myelin oligodendrocyte glycoprotein

MOG

0.49

0.0271

Down

2 (4,6)

plasma membrane proteolipid (plasmolipin)

PLLP

0.48

0.0285

Down

1 (1)

proteolipid protein 1

PLP1

0.46

0.0386

Down

2 (1,6)

myelin protein zero-like 1

MPZL1

-0.63

0.0063

Up

1 (6)

aspartoacylase

ASPA

0.48

0.0298

Down

1 (7)


Myelination related genes showing expression changes during adolescence and relevant findings from the schizophrenia literature are shown. Citations are indicated by a footnote in the final column as follows: 1 [46] 2. [47] 3. [48] 4. [49] 5[50] 6. [45] 7. [52]

Harris et al. BMC Medical Genomics 2009 2:28   doi:10.1186/1755-8794-2-28

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