ELM conservation on NEF. ELMs were spatially conserved on alignments of HIV-1 proteins of subtypes B and C. Each box shows the annotations for one conserved ELM (present on more than 70% of protein instances) on the multiple alignment of NEF proteins. An ELM can be spatially conserved in multiple positions on the alignment, demonstrated by multiple sets of thick vertical lines in an ELM's box.
Evans et al. BMC Medical Genomics 2009 2:27 doi:10.1186/1755-8794-2-27