Table 2

Clinical and molecular parameters of breast cancers. Clinical and molecular parameters are given for each breast cancer used in this study. Module scores for each tumor were calculated from the results based on intact RNA (FF material) and based on RNA isolated from FFPE material according to our own method. N.A., data not available.

Clinical classification

Immunohistochemistry

Module Score (FF/FFPE)


Tu#

T

N

Grade

ER

PR

ErbB2

ER

HER2

Prolif.

Histological type


2

2

0

3

70% pos.

neg.

1+

16.6/17.1

15.8/16.3

14.2/14.5

invasive ductal

3

2

1a

2

70% pos.

pos.

1+

17.2/17.7

16.4/16.6

14.3/14.0

mixed (duct./lob)

6

1c

3a

3

>90% pos.

pos.

3+

15.7/16.2

17.2/18.1

14.5/15.4

invasive ductal

8

2

2a

3

>90% pos.

pos.

2+

16.5/17.2

15.8/16.3

14.7/14.7

invasive ductal

10

1c

N.A.

2

>90% pos.

pos.

2+

14.5/16.6

15.2/16.2

13.5/14.4

invasive ductal

13

2

3a

3

>90% pos.

neg.

1+

16.6/17.0

15.7/15.6

14.6/14.5

invasive ductal

14

1c

N.A.

2

>90% pos.

neg.

1+

16.5/16.9

16.2/16.4

13.8/13.5

invasive ductal

15

N.A.

3

neg.

neg.

0

11.8/13.0

14.9/15.5

14.9/15.5

invasive ductal

16

2

N.A.

1

65% pos.

pos.

0

17.9/18.3

16.4/16.6

13.8/14.1

invasive ductal/cribriform

17

2

0

3

>90% pos.

pos.

2+

16.5/17.2

16.3/16.9

14.9/15.6

invasive ductal

18

2

N.A.

3

neg.

neg.

0

13.0/12.9

15.1/15.9

15.2/16.0

invasive ductal

19

2

N.A.

2

>90% pos.

pos.

0

17.2/17.6

15.9/16.0

13.8/14.2

invasive ductal

20

1c

N.A.

2

neg.

neg.

0

12.4/13.0

15.7/15.9

14.6/15.2

invasive ductal

22

2

0

2

N.A.

N.A.

N.A.

16.8/17.4

15.6/16.1

13.3/13.9

invasive ductal


Oberli et al. BMC Medical Genomics 2008 1:9   doi:10.1186/1755-8794-1-9

Open Data