Module scores. ER, HER2 and proliferation scores were computed from expression values of 14 breast cancers and visualized in a scatter plot. The ER score was determined from four genes, the HER2 score from 2 and the proliferation score from 5 genes (see Methods). Tumors are positioned according to their ER score (x-axis) and HER2 score (y-axis). Proliferation scores are color coded. The histological ER status is indicated by a "-" or "+" sign next to the tumor numbers in the plot. The results were computed from intact RNA derived of FF material (A) and RNA isolated from FFPE material according to our own protocol (B). Individual scores for each tumor are given in Table 2.
Oberli et al. BMC Medical Genomics 2008 1:9 doi:10.1186/1755-8794-1-9