|
Distribution of selected characteristics by genotypes for each ABCB1 variant in the Seychelles |
||||||
| 2677 G>T |
3435 C>T |
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|
|
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| GG |
GT |
TT |
CC |
CT |
TT |
|
|
|
||||||
| N |
191 |
84 |
15 |
132 |
118 |
40 |
|
|
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| Age (years) |
46.8 ± 12.2 |
46.2 ± 11.8 |
44.6 ± 12.5 |
46.0 ± 12.2 |
47.3 ± 11.5 |
45.8 ± 13.3 |
| Proportion of women |
0.57 ± 0.50 |
0.51 ± 0.50 |
0.47 ± 0.52 |
0.59 ± 0.49 |
0.51 ± 0.50 |
0.53 ± 0.51 |
| BMIa (kg/m2) |
28.0 ± 5.6 |
28.5 ± 5.0 |
26.8 ± 4.2 |
27.3 ± 5.2 |
29.0 ± 5.7 |
28.0 ± 4.9 |
| MAPb (mm Hg) |
101 ± 13 |
103 ± 14 |
98 ± 15 |
100 ± 14 |
103 ± 13 |
99 ± 14 |
| FBGc (mmol/L) |
4.6 ± 1.8 |
4.6 ± 1.7 |
4.5 ± 1.6 |
4.6 ± 1.6 |
4.7 ± 1.9 |
4.6 ± 1.5 |
| Diabetes (prevalence) |
0.08 ± 0.28 |
0.11 ± 0.31 |
0.07 ± 0.26 |
0.08 ± 0.27 |
0.09 ± 0.29 |
0.13 ± 0.33 |
| Plasma Na (mmol/L) |
140 ± 4 |
140 ± 4 |
139 ± 3 |
140 ± 4 |
140 ± 4 |
139 ± 3 |
| Plasma K (mmol/L) |
3.8 ± 0.3 |
3.7 ± 0.3 |
3.7 ± 0.4 |
3.7 ± 0.3 |
3.8 ± 0.3 |
3.7 ± 0.3 |
| Urine Na (mmol/24 h) |
106 ± 54 |
107 ± 56 |
104 ± 67 |
101 ± 54 |
108 ± 56 |
118 ± 57 |
| Urine K (mmol/24 h) |
44 ± 18 |
46 ± 18 |
35 ± 16 |
44 ± 17 |
45 ± 19 |
44 ± 17 |
|
Results presented are the mean ± s.d. For each variant, there was no significant trend across genotypes. aBMI: body mass index. bMAP: mean arterial pressure. cFBG: fasting blood glucose. | ||||||
Bochud et al. BMC Medical Genomics 2008 1:21 doi:10.1186/1755-8794-1-21 |
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