Table 2

Genes downregulated in palmar fascia fibroblasts obtained from Dupuytren's Contracture using CodeLinkā„¢ Platform.

Gene ID

Gene Name

Fold Change


1.

NM_002847

Protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1

0.16

2.

NM_021602

CD79B antigen (immunoglobulin-associated beta) (CD79B), transcript variant 2

0.18

3.

NM_001831

Clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1

0.21

4.

NM_004000

chitinase-3-like 2 (CHI3L2)

0.22

5.

NM_152536

FYVE, RhoGEF and PH domain containing 5 (FGD5), mRNA

0.25

6.

NM_000668

Alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B)

0.29

7.

NM_001831

clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1

0.30

8.

NM_005410

selenoprotein P, plasma, 1 (SEPP1)

0.34

9.

NM_005525

hydroxysteroid (11-beta)dehydrogenase 1 (HSD11B1), transcript variant 1

0.35

10.

NM_145244

DNA-damage inducible transcript 4-like (DDIT4L)

0.37

11.

NM_012168

F-box protein 2 (FBXO2), mRNA

0.38

12.

NM_021146

angiopoietin-like factor (CDT6)

0.39

13.

U83115

Non-lens beta gamma-crystallin like protein (AIM1)mRNA

0.42

14.

NM_001801

cysteine dioxygenase type1 (CDO1)

0.45

15.

NM_005627

serum/glucocorticoid regulated kinase (SGK)

0.49

16.

NM_002928

Regulator of G-protein signaling 16 (RGS16)

0.49

17.

NM_000690

aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), nuclear gene encoding mitochondrial protein

0.54

18.

NM_005391

pyruvate dehydrogenase kinase, isoenzyme 3 (PDK3)

0.55

19.

NM_000636

superoxide dismutase 2, mitochondrial (SOD2)

0.56

20.

NM_006391

Importin 7 (IPO7)

0.57

21.

NM_030968

C1q and tumor necrosis factor related protein 1 (C1QTNF1), transcript variant 1

0.58

22.

NM_001353

aldo-keto reductase family 1, member C1 (dihyrdodiol dehydrogenase 1;20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1)

0.59


cDNA of Unknown Biological Function


1.

D52654

HUM084D02B Clontech human fetal brain polyA+ mRNA (#6535) cDNA clone GEN-084D02 5'

0.00

2.

AI597810

tu91f07x1 NCI_CGAP_Gas4 cDNA clone IMAGE:2258437 3' similar to contains L1.t1 L1 L1 repetitive element;

0.01

3.

H90897

yu89c07s1 Soares fetal liver spleen 1NFLS cDNA clone IMAGE:240972 3'

0.10

4.

NM_021602

CD79B antigen (immunoglobulin-associated beta) (CD79B), transcript variant 2

0.18

5.

BX094389

NCI_CGAP_Ut4 cDNA clone IMAGp998O234898

0.23

6.

NM_152536

FYVE, RhoGEF and PH domain containing 5 (FGD5), mRNA

0.25

7.

AK054990

cDNA FLJ30428 fis, clone BRACE2008941

0.31

8.

AA866107

oh53b03.s1 NCI_CGAP_GC4 cDNA clone IMAGE:1470317 3'

0.33

9.

BU624020

UI-H-FG1-bgh-h-24-0-UIs1 NCI_CGAP_FG1 cDNA clone UI-H-FG1-bgh-h-24-0-UI 3'

0.34

10.

AI186220

qd34a02x1 Soares_fetal_heart_NbHH19W cDNA clone IMAGE:1731338 3'

0.35

11.

BG117761

602350442F1 NIH_MGC_90 cDNA clone IMAGE:4445147 5'

0.40

12.

BM929454

UI-E-EJ1-aje-b-23-0-UIr1 UI-E-EJ1 cDNA clone UI-E-EJ1-aje-b-23-0-UI 5'

0.42

13.

AL117425

mRNA; cDNA DKFZp566L203 (from clone DKFZp566L203)

0.43

14.

BQ430788

AGENCOURT_7776027 NIH_MGC_68 cDNA clone IMAGE:6024295 5'

0.44

15.

AA594928

no40a05s1 NCI_CGAP_Pr23 cDNA clone IMAGE:1103120 3'

0.46

16.

H05195

yl85f06r1 Soares infant brain 1NIB cDNA clone IMAGE:45005 5'

0.47

17.

AK124841

cDNA FLJ42851 fis, clone BRHIP2005719

0.47

18.

H05195

yl85f06r1 Soares infant brain 1NIB cDNA clone IMAGE:45005 5'

0.48

19.

AL119769

DKFZp761E1224_r1 761 (synonym: hamy2) cDNA clone DKFZp761E1224 5'

0.54

20.

AI094001

qa28a03s1 Soares_NhHMPu_S1 cDNA clone IMAGE:1688044 3'

0.54

21.

AL133055

mRNA; cDNA DKFZp434J1015 (from clone DKFZp434J1015)

0.56

22.

BX094154

Soares fetal liver spleen 1NFLS cDNA clone IMAGp998P17654

0.58

23.

W67378

zd40b03r1 Soares_fetal_heart_NbHH19W cDNA clone IMAGE:343085 5' similar to SW:DHAM_HUMAN P05091 ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR;

0.58

24.

BM829211

K-EST0102153 S9SNU601 cDNA clone S9SNU601-57-C10 5'

0.58

25.

BM711907

UI-E-CL1-afc-i-20-0-UIr1 UI-E-CL1 cDNA clone UI-E-CL1-afc-i-20-0-UI 5'

0.59

26.

BX088944

Soares_testis_NHT cDNA clone MAGp998J113516; IMAGE:1392490

0.72

27.

BC033399

clone IMAGE:4829538

0.77

28.

CB960582

AGENCOURT_13892014 NIH_MGC_147 cDNA clone IMAGE:30343321 5'

0.79

29.

BC034566

clone IMAGE:4821877, mRNA

0.79


SAM analysis was performed to identify the statistically significant differentially expressed genes. Genes that are common to both platforms are highlighted as Bold and Italics.

Satish et al. BMC Medical Genomics 2008 1:10   doi:10.1186/1755-8794-1-10

Open Data