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This article is part of the supplement: Proceedings of the Great Lakes Bioinformatics Conference 2012

Open Access Proceedings

Identifying stage-specific protein subnetworks for colorectal cancer

Sinan Erten1*, Salim A Chowdhury2, Xiaowei Guan345, Rod K Nibbe3, Jill S Barnholtz-Sloan35, Mark R Chance356 and Mehmet Koyutürk135

Author Affiliations

1 Department of Electrical Engineering & Computer Science, Case Western Reserve University, Cleveland, OH, USA

2 School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA

3 Case Center for Proteomics & Bioinformatics, Case Western Reserve University, Cleveland, OH, USA

4 Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA

5 Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA

6 Department of Genetics, Case Western Reserve University, Cleveland, OH, USA

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BMC Proceedings 2012, 6(Suppl 7):S1  doi:10.1186/1753-6561-6-S7-S1

Published: 13 November 2012

Additional files

Additional file 1:

List of 9 statistically significant subnetworks identified for GSE14333 dataset. All the gene products in the 9 statistically significant subnetworks identified for GSE14333 dataset are listed, as well as the covered colorectal cancer stage and cover direction of the corresponding subnetworks. Please note that these gene products might not be direct neighbours in the PPI network, as we set the network distance parameter ℓ = 3 in the experiments.

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Open Data